Below is an interesting article regarding resveratrol, long life and Transfer factor from Mike.

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Q: Shaklee has a product called Vivix that is a revolutionary breakthrough. Will 4Life be bringing something out like Vivix?? Douglas

A: Hi Douglas,

Thank you for your question.

The key ingredient in Vivix is resveratrol. Resveratrol is a antioxidant found in grapes, red wine and other plants. There are several studies that indicate that resveratrol may extend a person's life.

Previously the only thing that has been proven in animal models to slow down the aging process or extend one's life is calorie restriction. In human studies there are indications that the same results may hold true as were found in animal studies. This has not been proven.

Studies at Harvard university indicate that resveratrol may have similar effects on animal models. Resveratrol may activate molecular pathways involved in life-span extension similar to mechanisms responsible for results in animal studies with calorie restriction. So far these results have only been proven in yeast, worms, flies, fish, and mice.

These studies were conducted on animals that were feed excessive amounts of calories and them given reservatrol. The animals feed resveratrol didn't experience the complications that generally accompany excessive consumptiom of calories. These animals lived 70% longer.

The question is does calorie restriction or resveratrol slow down the actual aging process or reduce excelerated aging caused by excessive eating. Excessive eating can cause a number of health conditions that will shorten a person's life. Some of the benefits of resveratrol may be:


increased insulin sensitivity
lower blood sugar
enhanced mitochondrial energy production
improved motor function.

There are indications that resveratrol influences many genetic pathways, which may underlie its ability to lengthen life. In the recent Harvard study, investigators noted that a high-calorie diet produced numerous changes in gene expression. However, supplemental resveratrol opposed the effects of this high-calorie diet in 144 of 153 significantly altered genetic pathways. Resveratrol’s effects were dose dependent, with larger amounts yielding greater effects. Drinking two glasses of red wine a day doesn't match the dosages used in the studies. Drinking more than two glasses can cause serious health challenges.

An area that both caloric restriction and resveratrol had similar effects was with long-term activation of AMP-activated kinase (AMPK), a metabolic enzyme promoting insulin sensitivity and fatty-acid oxidation. Increasing AMPK activity is associated with life-span extension.

Scientists believe that caloric restriction increases life span in part through its effects on the sirtuin genes.5 Present in all life forms, sirtuin genes are associated with aging and longevity. Resveratrol may produce benefits similar to those of caloric restriction by influencing the sirtuin gene known as SIRT2.5,8-10 In the Harvard study, resveratrol helped counteract changes in SIRT2 expression induced by a high-calorie diet.

Sirtuins are a class of histone deacetylase enzymes (HDACs) involved in cell death and life-span regulation.
Researchers believe that compounds like resveratrol that either activate or inhibit sirtuin activity

In numerous studies, restricting calorie intake and consuming reservatrol in laboratory animals has been shown to prolong their life span by as much as 60% - 70%. While scientists have not yet determined whether caloric restriction or resveratrol extends life span in humans, the preliminary evidence is very promising. In humans, consuming a low-calorie diet is associated with several possible markers of greater longevity, such as lower insulin levels and reduced body temperatures, along with less of the chromosomal damage that typically accompanies aging. Furthermore, people who consume a low-calorie diet may be less prone to diseases associated with being overweight or obese, such as metabolic syndrome, diabetes, cancer, and atherosclerosis.

There is one concern in consuming resveratrol. Resveratrol inhibits the liver enzyme P450, which clears the body of medicines such as statin drugs, Calcium blockers (for high blood pressure) and benzodazopims. Resvertrol could cause you to over dose on your medicines. It would cause the medicine to stay in your body longer. For example if you are consuming a medicine on a daily basis, the manufacture calculates how much of the medicine is cleared from your body each day. Your daily dose is calculated on this basis. With resveratrol in your body you would keep more of the medicine in your body each day than the manufacture anticipated. Eventually you would over dose on the medicine.

Also one of the pathways that resveratrol uses is to prevent angiotensin 2 from producing myofibroblast that causes the body to produce more collagen. This is good for a heart attack victim but the question is how does it effect the production of collagen other places in the body. There is a up side and a down side. The key is to consume moderately.

I consume resveratrol daily. The cost of Vivix is much higher than purchasing resveratrol from Life Extension Foundation or even a local nutritional store. There are many products containing resveratrol. Riovida having grapes should contain resveratrol. Vivix may not be a great product to base your future residual income on because your distributors an customers can purchase high quality resveratrol at a more reasonable cost many other places.


The only nutritional product that has been found in human studies to reverse some age and to slow down the aging process is Transfer Factor. A study released by a European life extension symposium and conducted by Russian scientists found the by consuming 4Life's Transfer Factor for six weeks the participants experience a reduction in biological age by four years. Now this is real anti aging news! Why mess with Vivix containing resveratrol that only animal studies have found a reduction in age when you can get the real thing proven in human studies, TRANSFER FACTOR! Be blessed. Mike

Ref: http://www.professionalnetworkers.com/forum/viewtopic.php?t=12993&sid=70d847e471f6148839ed812594c82bcf